水口貴仁先生の論文が、Digestive endoscopy (Journal Citation Reports Impact Factor 2020 = 7.559)にacceptされました。
Dig Endosc. 2022 Feb 2. doi: 10.1111/den.14261. Online ahead of print.
Measuring optimal ultrasound speed using endoscopic ultrasound in patients with chronic pancreatitis, including early stage
Takahito Minaguchi, Akira Yamamiya, Keiichi Tominaga, Ken Kashima, Yasuhito Kunogi, Fumi Sakuma, Koh Fukushi, Kazunori Nagashima, Naoya Izawa, Akane Yamabe, Koki Hoshi, Makoto Iijima, Kenichi Goda, Yasuo Haruyama, Atsushi Irisawa
PMID: 35108413 DOI: 10.1111/den.14261
Background and aim: Ultrasound speed (USS) correction improves image quality by estimating the optimal USS correcting the deviation from a predetermined USS. This study assessed USS differences between CP, early CP (ECP), and normal pancreas when using EUS. The usefulness of measuring optimal USS was evaluated for patients with CP, including early stage patients.
Method: This study enrolled 116 consecutive patients for whom USS was measured using an EUS system. The USS correction principle is generation of a B-mode image by changing the USS in all ranges while correcting the delay in the received data. Final diagnoses were made according to the Japanese diagnostic criteria for CP in 2019. They were classified as CP, ECP, or normal. We compared USS applied for these three groups.
Results: The medians and ranges USS values for patients in the normal, ECP, and CP groups were, respectively, 1506.0 (1407-1600) m/s, 1580.0 (1520-1630) m/s, and 1574.0 (1537-1610) m/s. The USS values of ECP and CP groups were significantly higher than those of the normal group (p< .001). Analyses of the ROC curve in the normal pancreas, ECP, and CP revealed the area as 0.957, with specificity and sensitivity of 95.9% and 87.5%, respectively, using the USS of 1535 m/s as a cutoff.
Conclusions: Measurement of USS might be particularly useful for distinguishing between normal and ECP imaging.
Keywords: chronic pancreatitis; early chronic pancreatitis; endoscopic ultrasound; ultrasound speed.