業績報告 【publish】飯島誠 先生 有阪高洋 先生 Diagnostics誌

飯島誠先生と有阪高洋先生の共著論文が、Diagnostics誌(Journal Citation Reports Impact Factor 2019 = 3.110)にpublishされました。

Feasibility and Safety of Transjugular Liver Biopsy for Japanese Patients with Chronic Liver Diseases

Makoto Iijima, Takahiro Arisaka, Akira Yamamiya, Keiichi Tominaga, Kazunori Nagashima, Akira Kanamori, Satoshi Masuyama, Yuichi Majima , Kenichi Goda, Kazuyuki Ishida, Atsushi Irisawa

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PMID: 33467069 DOI: 10.3390/diagnostics11010131

Abstract
Background and study aim: Transjugular liver biopsy (TJLB) can be used in patients who are ineligible for percutaneous liver biopsy (PLB) with acute and chronic hepatic disease. This study aimed to evaluate the usefulness and safety of TJLB in patients who were not indicated for PLB.

Methods: Between July 2014 and February 2019, a total of 134 patients underwent liver biopsies at our institution. Among these, PLB was performed in 110 patients and TJLB in 24 patients. A retrospective comparison of clinical results in these patients was then performed. The primary endpoints of this study were the utility and safety of TJLB in patients who were not indicated for PLB.

Results: The procedural success rate was 100% in both groups. The clinical response rate and the effective tissue sampling rate were 100% in the TJLB group and 97% in the PLB group (p = 0.55). There was no difference in the number of portal fields examined retrospectively between the two groups. No serious adverse events were observed in either group.

Conclusions: It is suggested that TJLB is useful because it can be safely performed in patients with poor general condition who are not indicated for PLB.

Keywords: acute hepatic disease; chronic hepatic disease; percutaneous liver biopsy; transjugular liver biopsy.