山崎ゆうか先生の症例報告論文が、Internal Medicine（Journal Citation Reports Impact Factor 2023 = 1.0）にpublishされました。

Intern Med. 2024 Dec 19. doi: 10.2169/internalmedicine.4720-24. Online ahead of print.

Acute Liver Failure Caused by Isoniazid during Preventive Treatment for Latent Tuberculosis: A Rare Autopsy Case Report

Yuka Yamazaki, Keiichi Tominaga, Takahiro Arisaka, Mayuko Tagaya, Shunsuke Kojimahara, Toshihiko Ohnishi, Yuichi Majima, Akira Yamamiya, Makoto Iijima, Naoya Ikeda, Seiji Niho, Shuhei Noda, Kazuyuki Ishida, Atsushi Irisawa

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PMID: 39694482 DOI: 10.2169/internalmedicine.4720-24
Free article

Abstract
Treating patients with latent tuberculosis infection (LTBI) to prevent the development of tuberculosis is a fundamental treatment strategy in daily practice. Isoniazid (INH) therapy for 6-12 months is recommended. However, INH can also cause hepatotoxicity. This report describes the autopsy case of a 65-year-old Japanese man diagnosed with LTBI who died of acute liver failure caused by INH.

Keywords:acute liver failure; autopsy; isoniazid; latent tuberculosis infection; tuberculosis.

https://pubmed.ncbi.nlm.nih.gov/39694482/